Welcome to FIS   Sponsored By
Subscribe to FIS | Register with FIS | Advertise with FIS | Newsletter | About FIS | Contact us
   


Anchovy is one of the omega-3 oil richest fish. (Photo: NOAA / FIS)(Photo Credit: NOAA/FIS)

Omega-3 fatty acids may provide more benefits than thought

Click on the flag for more information about United States UNITED STATES
Monday, January 27, 2014, 22:50 (GMT + 9)

A study of the metabolic effects of omega-3 fatty acids, especially DHA, concludes that these compounds may have an even wider range of biological impacts than previously considered, and suggests they could be of significant value in the prevention of fatty liver disease.

The research, done by scientists at Oregon State University and several other institutions, was one of the first of its type to use “metabolomics,” an analysis of metabolites that reflect the many biological effects of omega-3 fatty acids on the liver. It also explored the challenges this organ faces from the “Western diet” that increasingly is linked to liver inflammation, fibrosis, cirrhosis and sometimes liver failure.

The findings, which researchers say were surprising, were published last month in PLOS One.

Supplements of DHA, used at levels that are sometimes prescribed to reduce blood triglycerides, appeared to have many unanticipated effects. There were observable changes in vitamin and carbohydrate metabolism, protein and amino acid function, as well as lipid metabolism.

Supplementation with DHA partially or totally prevented metabolic damage through those pathways often linked to the Western diet – excessive consumption of red meat, sugar, saturated fat and processed grains.

“We were shocked to find so many biological pathways being affected by omega-3 fatty acids,” said Donald Jump, a professor in the OSU College of Public Health and Human Sciences. “Most studies on these nutrients find effects on lipid metabolism and inflammation.

“Our metabolomics analysis indicates that the effects of omega-3 fatty acids extend beyond that, and include carbohydrate, amino acid and vitamin metabolism,” he added.

Omega-3 fatty acids have been the subject of much recent research, often with conflicting results and claims. Possible reasons for contradictory findings, OSU researchers say, are the amount of supplements used and the relative abundance of two common omega-3s – DHA and EPA. Studies at OSU have concluded that DHA has far more ability than EPA to prevent the formation of harmful metabolites. In one study, it was found that DHA supplementation reduced the proteins involved in liver fibrosis by more than 65 percent.

These research efforts, done with laboratory animals, used a level of DHA supplementation that would equate to about 2-4 grams per day for an average person. In the diet, the most common source of DHA is fatty fish, such as salmon, mackerel or sardines.

The most recent research is beginning to break down the specific processes by which these metabolic changes take place. If anything, the results suggest that DHA may have even more health value than previously thought.

“A lot of work has been done on fatty liver disease, and we are just beginning to explore the potential for DHA in preventing or slowing disease progression,” said Jump, who is also a principal investigator in OSU’s Linus Pauling Institute.

“Fish oils, a common supplement used to provide omega-3, are also not prescribed to regulate blood glucose levels in diabetic patients,” he said. “But our studies suggest that DHA may reduce the formation of harmful glucose metabolites linked to diabetic complications.”

Both diabetes and liver disease are increasing steadily in the United States.

The American Liver Foundation has estimated that about 25 per cent of the nation’s population, and 75 percent of those who are obese, have nonalcoholic fatty liver disease. This can progress to nonalcoholic steatohepatitis, cirrhosis and cancer.

This study established that the main target of DHA in the liver is the control of inflammation, oxidative stress and fibrosis, which are the characteristics of more progressively serious liver problems. Omega-3 fatty acids appear to keep cells from responding to and being damaged by whatever is causing inflammation.
 

Source: Oregon Statate University

[email protected]
www.fis.com


 Print


Click to know how to advertise in FIS
MORE NEWS
United States
May 22, 03:20 (GMT + 9):
Lobster exporters fear China's retaliation for tariff implementation
Vanuatu
May 22, 02:40 (GMT + 9):
Tuna plant restarts operations thanks to Chinese funding
Spain
May 22, 02:20 (GMT + 9):
Andalusia demands management plan to increase bluefin tuna catch
Oman
May 22, 02:10 (GMT + 9):
First sea bream project harvest begins
United Kingdom
May 22, 01:00 (GMT + 9):
IFFO RS seeks to improve its standard
Spain
May 21, 23:20 (GMT + 9):
Bermeo launches global initiative for tuna sustainability
Chile
May 21, 22:20 (GMT + 9):
New MSC standard for seaweed presented
United States
May 21, 22:00 (GMT + 9):
IN BRIEF - Governor says another Chinese company wants to invest in Maine
Mexico
May 21, 21:30 (GMT + 9):
MSC deems Mexico is Latin America leader in fisheries sustainability
United States
May 19, 03:10 (GMT + 9):
First Copper River salmon arrives at Seattle with high prices
Argentina
May 19, 02:20 (GMT + 9):
Fresh shrimp fleet could stop operations
Canada
May 19, 02:10 (GMT + 9):
Climate change to affect commercial fishermen in the US and Canada
Canada
May 19, 02:00 (GMT + 9):
IN BRIEF - Report: Canadian salmon firm admits using lobster-killing pesticide near Maine border
Japan
May 19, 02:00 (GMT + 9):
IN BRIEF - Fish recycling program begins at conveyor-belt sushi chain Kurazushi
United States
May 19, 02:00 (GMT + 9):
IN BRIEF - Cooke Aquaculture To Create Up to 100 New Jobs



Lenguaje
FEATURED EVENTS
  
TOP STORIES
First Copper River salmon arrives at Seattle with high prices
United States The fishery for Copper River king salmon opened in Alaska on Thursday and the first shipment of fish arrived with much fanfare at Sea-Tac Airport, Washington, Friday morning.
Govt to aid sector to restart exports to Saudi Arabia
Myanmar The Myanmar government expressed its intention to join efforts with private seafood factories to restart fish and shrimp exports to Saudi Arabia after the ban imposed by Saudi authorities in April.
EU to keep yellow card for Thailand
Thailand The European Union has decided to keep a yellow card for Thailand over the country’s illegal, unreported and unregulated fishing problems, a source at the Agriculture and Cooperatives Ministry revealed.
Chamber of Deputies approves bill regulating giant squid capture
Chile With a strong support and in front of a wide citizenship attendance, including representatives of the artisanal and industrial fishing sectors, the Room of the House of Representatives approved in general the bill regulating giant squid capture.
 
Maruha Nichiro Corporation
Nichirei Corporation -Headquarter-
Pesquera El Golfo S.A.
Ventisqueros - Productos del Mar Ventisqueros S.A
Wärtsilä Corporation -Wartsila Group Headquarter-
ITOCHU Corporation -Headquarter-
BAADER - Nordischer Maschinenbau Rud. Baader GmbH+Co.KG (Head Office)
Inmarsat plc - Global Headquarters
Marks & Spencer
Tesco PLC (Supermarket) - Headquarters
Sea Harvest Corporation (PTY) Ltd. - Group Headquarters
I&J - Irvin & Johnson Holding Company (Pty) Ltd.
Blue Continent Products (Pty) Ltd - (Oceana Group Limited)
Pesquera San Jose S.A.
Nutreco N.V. - Head Office
CNFC China National Fisheries Corporation - Group Headquarters
W. van der Zwan & Zn. B.V.
SMMI - Sunderland Marine Mutual Insurance Co., Ltd. - Headquarters
Icicle Seafoods Inc. -Headquarter-
Starkist Seafood Co. - Headquearters
Trident Seafoods Corp.
American Seafoods Group LLC - Head Office
Marel - Group Headquarters
SalMar ASA - Group Headquarters
Sajo Industries Co., Ltd
Hansung Enterprise Co.,Ltd.
BIM - Irish Sea Fisheries Board (An Bord Iascaigh Mhara)
CEFAS - Centre for Environment, Fisheries & Aquaculture Science
COPEINCA ASA - Corporacion Pesquera Inca S.A.C.
Chun Cheng Fishery Enterprise Pte Ltd.
VASEP - Vietnam Association of Seafood Exporters & Producers
Gomes da Costa
Furuno Electric Co., Ltd. (Headquarters)
NISSUI - Nippon Suisan Kaisha, Ltd. - Group Headquarters
FAO -Food and Agriculture Organization- Fisheries and Aquaculture Department (Headquarter)
Hagoromo Foods Co., Ltd.
Koden Electronics Co., Ltd. (Headquarters)
A.P. Møller - Maersk A/S - Headquarters
BVQI - Bureau Veritas Quality International (Head Office)
UPS - United Parcel Service, Inc. - Headquarters
Hamburg Süd Group - (Headquearters)
Armadora Pereira S.A. - Group Headquarters
NOAA - National Oceanic and Atmospheric Administration (Headquarters)
Omega Protein Corporation -Headquarter-
Marona S.A.
Marine Harvest ASA - Headquarters
Marubeni Europe Plc -UK-
Findus Ltd
Icom Inc. (Headquarter)
WWF Centroamerica
Oceana Group Limited
The David and Lucile Packard Foundation
Ajinomoto Co., Inc. - Headquarters
Friosur S.A. - Headquarters
Cargill, Incorporated - Global Headquarters
Benihana Inc.
Leardini Pescados Ltda
Mitsubishi Corporation Marine Products Depts. D.Team
CJ Corporation  - Group Headquarters
Greenpeace International - The Netherlands | Headquarters
David Suzuki Foundation
Fisheries and Oceans Canada -Communications Branch-
Mitsui & Co.,Ltd - Headquarters
NOREBO Group (former Ocean Trawlers Group)
Natori Co., Ltd.
Carrefour Supermarket - Headquarters
FedEx Corporation -Headquarter-
AKBM - Aker BioMarine ASA
Seafood Choices Alliance -Headquarter-
Austevoll Seafood ASA
Walmart / Wal-Mart Stores, Inc. (Supermarket) -Headquarter-
New Japan Radio Co.Ltd (JRC) -Head Office-
Gulfstream JSC
INVE Group - Head Office
Marine Stewardship Council - MSC Worldwide Headquarters
Royal Dutch Shell plc (Headquarter)
Genki Sushi Co.,Ltd -Headquarter-
Iceland Pelagic ehf
AXA Assistance Argentina S.A.
Caterpillar Inc. - Headquarters
Tiger Brands Limited
Morpol ASA - Group Headquarters
SeaChoice
National Geographic Society
AmazonFresh, LLC - AmazonFresh

Copyright 1995 - 2018 Fish Info & Services Co.Ltd| All Rights Reserved.   DISCLAIMER