Bionaturis laboratory. (Photo: Bionaturis)
New antimicrobial product patent requested for aquaculture
Wednesday, May 29, 2013, 23:30 (GMT + 9)
A team of researchers from the Universidad Complutense de Madrid (UCM) and biopharmaceutical company Bionaturis requested the Spanish Patent and Trademark Office (SPTO) a patent for a new antimicrobial product that is specific for the inhibition of Lactococcus garvieae.
This bacterium produces lactococcosis disease, which represents a major health and economic problem for Spanish aquaculture, especially for trout production.
Bionaturis highlights that this antimicrobial compound "combats resistance and specificity issues experienced by the industry and that has led the WHO to include antibiotic resistance in the list of utmost surveillance priorities."
The bacterium Lactococcus garvieae is potentially zoonotic and causes different clinical processes such as endocarditis, and even septicemia to human beings.
Scientists of the departments of Animal Health and Nutrition, Food Science and Food Technology of the Veterinary Medicine School of the UCM are involved in this initiative.
The experts managed to purify and characterize a new bacteriocin (antimicrobial peptide with bactericidal activity), which is highly efficient and selective in the L. garvieae inhibition.
The initial work on the protection against the bacteriocin in experimental infections in zebrafish, performed with the company Bionaturis, proved successful.
Javier Gallastegui, the firm general manager, stressed that the drug has a high specificity and does not alter the rest of the bacterial flora that is beneficial to the organism.
"At the same time, it offers alternatives to traditional antibiotics where resistance phenomena are concerning, and quite a lot, for the health authorities," the executive added.
The research projects are funded with projects of the Ministry of Economy and Competitiveness.
The results of this study will be published in the international scientific journal Applied and Environmental Microbiology.
By Analia Murias